PCR170 Excessive Daytime Sleepiness and Sleep Quality and Their Impact on Health-Related Quality of Life in Epilepsy Patients: A Study from Pakistan

Epilepsy is one of most common but manageable neurological disorder. The relation between epilepsy, sleep and health-related quality life (HRQoL) in culturally distinct environment Pakistan remains unclear. purpose this study was to determine prevalence predictors excessive daytime sleepiness (EDS), poor (SQ), analyze their association with HRQoL people epilepsy (PWE). A conducted among PWE attending two tertiary care hospitals Islamabad Rawalpindi, Pakistan. EDS, SQ, were evaluated by Urdu versions Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI) Life Epilepsy-31 (QOLIE-31). included 200 51 healthy controls mean (SD) ages 33.1± 13.9, 32.9±10.9, a disease duration 5.01±6.17, respectively. majority the respondents (n= 130, 65%) had seizure control, these 88, 68%) on combination antiepileptic drug (AED) therapy. In comparison controls, higher number EDS ESS (score ≥11, 10% vs. 40%, p-value 0.00), SQ PSQI >5, 9% 71%, 0.00). multiple logistic regression analysis reveals factors significantly associated were: female gender; increasing age; control; epilepsy; AED second binary suggest that are Hierarchical multivariate analysis, EDS; significant low HRQoL. findings high negative exists complaints During routine clinical consultations, awareness about hygiene practices must be provided enhance